Located in Boston, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases.Â Â
TheÂ Center for Immuno-OncologyÂ established the Immune Assessment Laboratory to assist investigators at Dana-Farber Cancer Institute, its partners and external sites in establishing mechanistic and biomarker endpoints for clinical studies. With the recent success of immunotherapies through vaccines and checkpoint blockade targeted monoclonal antibodies, the goal of our Laboratory is to provide researchers with access to the latest innovations in immune monitoring in a quality-controlled setting.
The Lab offers technical support and scientific advice to investigators at Dana-Farber Cancer Institute and its partners who are interested in performing clinical studies related to cancer immunotherapies.
We provide data generation for clinical trials across multiple disease centers as well as the necessary expertise to design and develop assays related to cancer immunology biomarkers.
We are also involved in the collection of blood and solid tissue from patients participating in more than 30 clinical trials at DFCI as well as multiple external sites.
Our Lab is equipped with the latest technologies for the detection of soluble biomarkers, next generation sequencing, as well as determining cellular phenotypes.
Prepares and maintains tissue cultures
Operates instruments and equipment such as spectrophotometer, centrifuges, fluorimeter, incubators and light microscopes
Perform protein detection techniques such as ELISAs and flow cytometry
Manages and maintains database containing experimental results and reagent information and storage locations
Conducts literature reviews to assist in determining most suitable methods to be used in research
Prepares and presents written or oral progress reports concerning studies, including assembly, organization and interpretation of data
Performs statistical analysis of data
Prepares laboratory reagents, chemicals, instruments and equipment
Orders chemicals, reagents and other laboratory supplies
Performs routine maintenance and minor repairs of laboratory apparatus and instruments
Maintains a clean, orderly work area within the laboratory
Undertakes standard decontamination procedures prior to disposal of certain laboratory materials
Functions as the laboratory safety officer, responsible for compliance with all regulatory requirements, and the safe use of hazardous materials in the laboratory, including radioactive, biological and chemical agents
May demonstrate and explain various laboratory techniques to laboratory personnel, students and others
Maintains established department policies, procedures and objectives, including the areas of quality assurance, safety, environmental and infection control
Performs all other duties and responsibilities as directed
Graduate degree in Biology or healthcare related science
Preparation of media, tissue culture and assays reagents
Blood handling, and immune cells isolation and purification related techniques is a plus
Experience in cell culture techniques including culture, maintenance and storage of mammalian cell lines
ELISAs and flow cytometry experience (preferred)
Keep regular, detailed and accurate documentation of lab activities
Knowledge of Microsoft Word, Excel and other Windows-based software
Demonstrates exceptional organizational, communication and interpersonal skills
The successful candidate will be a team-oriented, bench scientist. He or she must be self-motivated, and detail-oriented. The candidate should be an effective communicator
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.
Internal Number: 2021-22445
About Dana-Farber Cancer Institute
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to under-served members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.