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Posted Job Title
Associate Director, Downstream Vector Services
Job Profile Title
Associate Director E
Job Description Summary
The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.Â
The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the âœgo-toâ organization for public and private partners, who want to participate in the gene therapy space. Currently we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.
Our Vector Core is a state-of-the-art facility which provides vector-related materials and services in support of basic and translational research worldwide.Â
The Vector core is on the hunt for an Associate Director of Downstream Vector Services (AD-DVS) to manage the downstream manufacturing of clinical vectors for internal clinical studies. Â
As the AD-DVS, you oversee and participate in downstream manufacturing, process optimization, and process development efforts for clinical-grade Adeno-Associated Viral Vectors (AAV). You will manage and lead the activities of a small team of downstream technologists, manage tech transfer activities with sponsors and CMO's, and interface with external sponsors.Â
This position is contingent on funding.
â¢ Masters Degree in Biology, Virology, Immunology, biomedical engineering or related field with 5-7 years relevant academic (e.g. post-doctoral) or industrial experience required (or combination) â¢ PhD strongly preferredÂ â¢ Extensive knowledge of downstream manufacturing and process development of biologics â¢ Must have experience with chromatography, TFF, and other filtration/purification techniques â¢ Ability to manage multiple projects, supervise staff and work collaboratively to achieve goals required â¢ Excellent oral/written communication skills required
Job Location - City, State
Department / School
Perelman School of Medicine
$72,837.00 - $138,391.00
Affirmative Action Statement Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.
Special Requirements Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
Internal Number: JR00012385
About University of Pennsylvania
Penn has a long and proud tradition of intellectual rigor and pursuit of innovative knowledge, begun by Benjamin Franklin in 1740. That tradition lives today through the creativity, entrepreneurship, and engagement of our faculty, students, and staff. Academic life at Penn is unparalleled, with an undergraduate student body of 10,000 from every U.S. state and around the world. The entering class of 2015 is the most talented and diverse in Penn's history. Consistently ranked among the top 10 universities in the country, Penn welcomes an additional 10,000 students to our top-ranked graduate and professional schools.