As a computational biologist at the Pancreatic Cancer Center for Excellence (PCCE), in close collaboration with bioinformaticians, biological scientists, and biotechnology technicians, you will focus on analyzing bulk, single-cell and spatial multi-omics data sets from pancreatic cancer patient tumors and disease models to investigate the gene function and regulatory networks driving the tumor and shaping its microenvironment. You will work with the data science and the biological lab teams to generate and analyze results of high-throughput assays to identify molecular mechanisms underpinning pancreatic-cancer tumorigenesis, progression, treatment resistance and metastasis. You must possess knowledge and have hands-on experience in analyzing sequencing data sets such as RNA-seq, ChIP-seq, ATAC-seq, DNase-seq, scRNA_seq, scATAC-seq, HiC, and GeoMx Spatial transcriptomics data sets. You must know molecular biology techniques like PCR, next-generation sequencing techniques (for example, library preparation for bulk and single-cell RNA-seq), histology, and flow cytometry. The candidate must be enthusiastic about preparing solutions, reagents, and media for cell culture and implementing computational biology workflows to address outstanding biological questions and generate meaningful insights into pancreatic cancer research. You must also possess the ability to adapt to project changes related to scope, schedule, workflow and/or system/process optimization needs as appropriate.
A vital enterprise in the nation’s heartland, the University of Nebraska Medical Center has its eye on improving the future of health care in Nebraska and beyond. As Nebraska’s only public academic health sciences center, UNMC is committed to the education of a 21st century health care work force, to finding cures and treatments for devastating diseases, to providing the best care for patients, and to serving our state and its communities through award-winning outreach. UNMC also is committed to embracing the richness of diversity, and is a major economic engine for the state of Nebraska. Led by Chancellor Jeffrey P. Gold, M.D., UNMC has six colleges, two institutes and a graduate studies program, serving nearly 4,000 students in more than two dozen programs. Our physician assistant program was recently ranked ninth in the nation by U.S. News & World Report, and our primary care program was ranked 17. The university’s physical therapy, pharmacy and public health programs also are ranked among the top in the country.
Read more about how this public academic health sciences center helps Nebraska.