The Rich Lab at the UNC Lineberger Comprehensive Cancer Center seeks multiple post-doctoral cancer biologists who will be passionate about cancer research with strong experimental skills in cell culture, molecular biology techniques, data analysis, and bioinformatics, and a good track of publication records in related areas to conduct basic and translational cancer research in the Dr. Jeremy Rich's laboratory for brain tumor studies. The goals of the Rich Lab are to identify novel therapeutic paradigms in the treatment of advanced cancers, primarily malignant brain tumors, through the prism of stem cell biology to identify core regulatory pathways amenable to pharmacologic targeting. The aim is to better understand the clinical relevance of cancer stem cells and the interaction with the tumor microenvironment and underlying genetic driver mutations in human cancers. The laboratory has made contributions in several areas, including therapeutic resistance, circadian rhythm, cancer epigenetics, tumor microenvironment, epitranscriptomics, tumor organoids/bioprinting, cancer metabolism, and cancer metabolism. A driving force in our research efforts is leveraging patient-derived tissues and collaborations with other research groups with complementary expertise. The Postdoc will conduct research in applying novel biomarkers to clinical trials, as well as cancer biology hypothesis testing. The position is one that has potential for growth into a leadership position. There is opportunity for collaboration with oncologists at nearby hospitals and with scientists at the Laboratory for Systems Pharmacology at Harvard Medical School.

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