Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch's global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.
At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.
The primary responsibility of a Cellular Production Associate I-II is to execute manufacturing operations in the production of modified cellular products for patients participating in clinical protocols using cellular therapy. Clinical manufacturing in the Cell Processing Facility (CPF) requires following applicable current Good Manufacturing Practices (cGMP) in a cleanroom processing environment.
Utilizing aseptic techniques, perform a variety of open cell product manipulations in an ISO 5 biosafety cabinet
Follow Standard Operating Procedures (SOPs) and complete required processing documentation such as production batch records
Perform cell processing operations such as cell selection/depletion, expansion, stimulation, transduction, cryopreservation, and patient infusion preparation
Review executed GMP records for compliance with procedure
Identify deviations from approved policies and procedures. Document deviation, investigate occurrence, and contribute to CAPA development
Maintain and operate primary process equipment, such as incubators, centrifuges, cell sorting/selection equipment, and controlled-rate freezers
Participate in problem-solving and troubleshooting for cell processing operations and equipment. Assist in the evaluation of current practices and operations and help to implement changes to improve performance
Contribute to Corrective and Preventative Actions (CAPA) completion, and assist in the execution of change controls
Participate in quality/compliance improvement and technical development projects
Develop training skills, train junior associates
Act as Protocol Champion on existing protocols, assessing materials readiness using a Bill of Materials
As Protocol Champion, report production status and production run summary data
Assess the need for batch record updates and manage document change requests
Bachelor's degree in a biological science or equivalent experience and a minimum of one year of postgraduate relevant lab experience required, preferably in cGMP manufacturing bioprocessing
Minimum of 3 years of postgraduate lab experience is required to qualify for the CPA II level with experience in production of cellular therapies and maintaining long-term T-cell lines/clones preferred
Experience with open aseptic processing, working in biosafety cabinets
Experience with fundamentals of cell culture
Must be able to work efficiently, with strong attention to detail in a highly regulated environment
Proficiency with standard computer programs (MS Office)
Must be able to support teamwork, and communicate effectively in a diverse team environment
Must demonstrate solid time management and organizational skills, and strong verbal and written communication
Must be able to wear clean room attire, surgical masks, and all required Personal Protective Equipment (PPE)
Must have the ability to stand and to work in a biosafety cabinet for long periods
Meets physical requirements of the job, as follows: can lift a minimum of 25 pounds and the ability to bend, reach, stretch, and climb ladders
Ability to work non-standard shifts and occasional weekend days or evenings
Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.
A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.
Our Commitment to Diversity
We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at firstname.lastname@example.org or by calling 206-667-4700.
At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.