The Ganesh lab is seeking talented Postdoctoral Research Fellow candidates for human genetics studies of cardiovascular disease. We are conducting gene discovery studies using genome sequencing, GWAS and transcript expression profiling methods to understand both common and rare vascular diseases. We use in vitro cellular and in vivo models to assess the functional significance of our genomic discoveries. Our studies are closely tied to the clinic, with human tissue and blood samples from meticulously phenotyped patients and thus candidates can expect to gain exposure to translational aspects of their research projects within a dynamic laboratory that is discovery and studying novel influences on disease using both dry-lab and wet-lab approaches. This position will emphasize approaches to study rare and polygenic variation contributing to disease risk as well as sequencing data analysis. We have several data sets and reagents already generated (exome sequencing, GWAS genotyping, cellular and mouse models) that provide a rich opportunity for productivity and publications for a highly motivated postdoctoral fellow.

Candidates should have publications in genomics or molecular genetics fields with an interest in human genetics. The ideal candidate is highly motivated to learn solid scientific methods and to write manuscripts and grant applications.

The laboratory is well-funded by multiple federal sources (NIH, DOD) and non-federal sources.

Under the guidance of the PI:

• Sequencing data study planning, data quality control, analysis and reporting
• Learn as needed new analysis methods
• Summarize and communicate results
• Apply for grant funding
• Prepare and submit manuscripts
• Maintain regulatory and data permissions
• Participate in regular lab meetings, institutional research meetings and national conferences

• PhD or MD degree
• Experience with genomic data handling and analysis
• Solid understanding of basic human genetics principles

• Experience with scientific writing

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

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Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

The University of Michigan is an equal opportunity/affirmative action employer.

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