Position Description The Department of Comparative Medicine has immediate availability for 1-Post-doctoral position for a 12-month service period in the University of Washington. The start date would be Fall/Winter 2021 or sooner. The overall goals of the laboratory are to define the roles of specific signaling proteins in the development, functions, and transformation of immune cells. Potential projects will focus on utilizing murine models to define how loss-of-function mutations in specific genes result in Primary Immunodeficiency Diseases (PIDs) and autoimmunity. Project 1 involves investigating the mechanisms of how LOF mutations in Fnip1 alter immunometabolism and lymphocyte development (see Park et al., Immunity (PMID 22608497); Park et al.,