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TECHNICAL ASSOCIATE , Computer Science and Artificial Intelligence Laboratory (CSAIL) , to work at the interface of computational and experimental work seeking to dissect the mechanisms underlying human disease genetics, experimentally validate and refine biological hypotheses, and generate new datasetsfor computational analysis. Applications include several human diseases, specifically neurodegenerative, neuropsychiatric, immune, and cancer. Will carry out molecular assays including chromatin immunoprecipitation (ChIP-seq), assay of transposase accessible chromatin (ATAC-seq), RNAsequencing (RNA-seq), and single-cell profiling (scRNA-seq and scATAC-seq); perform geneknockdowns and knockouts and CRISPR-Cas9 genome editing; implement high-level research objectives, applying advanced research practices in broad areas of assignments and related fields; and work closely with project coordinator, research scientists, and other researchers to plan project execution, prioritize tasks, and achieve agreed-upon goals.
Job Requirements REQUIRED : BSc or B.A. in biology or related field; experience performing molecular biology and next generation sequencing experiments; background in genetics, molecular biology, and gene regulation; excellent interpersonal and communication skills, including the ability to convey information to others and takes steps to ensure understanding and to share information in a clear and concise manner; and ability to dentify and select appropriate tools, data, and analysis techniques to diagnose problems and develop solutions. PREFERRED : molecular assays experience with chromatin immunoprecipitation (ChIP-seq), assay oftransposase accessible chromatin (ATAC-seq), and RNA sequencing; high-throughput assay experience; and experience with perturbation assays, including gene knockdowns and knockouts, regulatory element perturbations, and genome editing. Job #20451
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