A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

The human immunodeficiency virus (HIV) causes a lethal syndrome (acquired immunodeficiency syndrome) characterized by CD4+ T cell depletion and resultant immunodeficiency. HIV has caused a worldwide epidemic that has killed millions of people and continues to infect about 40,000 people each year in this country. The long-term goal of our research program is to provide improved treatments for people with HIV/AIDS. Existing therapies are highly effective at rendering viral particles non-infectious and thus reducing viral loads. However, none of the current drugs are capable of destroying infected cells. Many infected cells have short half-lives and die within days or months. Others, however, remain in a state that is resistant to the immune system and can persist for years. To provide better therapies, our focus has been on understanding the molecular mechanisms of viral persistence within cellular reservoirs. The development of drugs that will inhibit these pathways will bring us closer to a cure.

More information on Dr. Collins lab can be found here: https://collins.lab.medicine.umich.edu

• Responsible for the operation of a specialized laboratory within a department or research program
• Perform research either independently or with minimal supervision, providing data for manuscripts and grants
• Has an active role in the design, execution and outcome assessment of a research project.  Coordinates the collection and analysis of data. Develops, designs, and conducts complex experiments in line with a research plan and reviews results periodically with Dr. Collins or Val Terry. 
• Trains users in equipment operation and laboratory techniques. Explains and demonstrates technology and equipment capabilities, operations limitations and outcomes.
• Engaged in writing research support proposals and acquiring data from outside agencies. Acts as a liaison with the Sherman lab in another department for acquiring data and sharing information related to the Nef inhibitor research project.
• Provides input into the development of procedures and in research design.
• Purchase lab supplies/stocking and organizing lab
• Maintain lab equipment
• Analyze complex data using statistical approaches to identify significant differences
• Analyze and present journal articles at lab meeting
• Edit, write and/or review manuscripts, grants, and budgets
• Assist graduate students and postdoctoral fellows with specialized lab procedures such as cloning, cell purification, and flow cytometry
• Negotiate discounts with vendors
• Assist with regulatory and safety compliance

Experience with expressing HIV proteins in lentiviral and defective HIV based vectors, purifying primary T cells from human peripheral blood, and with confocal microscopy, western blotting and cloning. A strong interest in and commitment to advancing our understanding of viral disease pathogenesis is essential.

Bachelor's degree in science (microbiology or related field preferred) and 1-3 years’ experience required.

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

The University of Michigan is an equal opportunity/affirmative action employer.

U-M COVID-19 Vaccination Policy

COVID-19 vaccinations are now required for all University of Michigan students, faculty and staff across all three campuses, including Michigan Medicine.  This includes those working or learning remotely.  More information on this policy is available on the Campus Blueprint website or the U-M Dearborn and U-M Flint websites.