The human immunodeficiency virus (HIV) causes a lethal syndrome (acquired immunodeficiency syndrome) characterized by CD4+ T cell depletion and resultant immunodeficiency. HIV has caused a worldwide epidemic that has killed millions of people and continues to infect about 40,000 people each year in this country. The long-term goal of our research program is to provide improved treatments for people withHIV/AIDS. Existing therapies are highly effective at rendering viral particles non-infectious and thus reducing viral loads. However none of the current drugs are capable of destroying infected cells. Many infected cells have short half-lives and die within days or months. Others, however, remain in a state that is resistant to the immune system and can persist for years. To provide better therapies, our focus has been on understanding the molecular mechanisms of viral persistence within cellular reservoirs. The development of drugs that will inhibit these pathways will bring us closer to a cure.
Perform research either independently or with minimal supervision, providing data for manuscripts and grants
Analyze complex data using statistical approaches to identify significant differences
Analyze and present journal articles at lab meeting
Edit, write and/or review manuscripts, grants, and budgets
Depending on stage and productivity there will be opportunities to participate in assembling manuscripts and attending national meetings
Assist graduate students and postdoctoral fellows with specialized lab procedures such as cloning, cell purification and flow cytometry
Purchase lab supplies/stocking and organizing lab
Negotiate discounts with vendors
Maintain lab equipment
Assist with regulatory and safety compliance
Bachelor's degree in science required, advanced degree beneficial. Strong fundamental understanding of biology and chemistry required. Working knowledge of laboratory best practices is essential. Experience with viral vectors including retroviral vectors, nucleic acid extraction and PCR is beneficial. A strong interest in and commitment to advancing our understanding of viral disease pathogenesis is essential.
Senior Level: 5-6 years of experience required, 2-5 years experience with cell culture is needed.
Intermediate Level: 4-5 years of experience required, 2-5 years experience with cell culture is needed.
This position may be underfilled at a lower classification depending on the qualifications of the selected candidate.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.
The University of Michigan is an equal opportunity/affirmative action employer.
U-M COVID-19 Vaccination Policy
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A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.