Principal Investigator, David Casero, PhD is looking for a Project Scientist to join the team!
The Inflammatory Bowel and Immunobiology Research Institute (IBIRI) is a multidisciplinary basic, translational and clinical research program devoted to discovering the causes of Inflammatory Bowel Disease (IBD) with the goal of improved treatment approaches and prevention. The laboratory of Dr. David Casero is looking for highly motivated computational scientists who are passionate about diving into complex biological data!
The group of Dr. David Casero applies Bioinformatics, Computational Biology and high-throughput sequencing data to analyze gene regulatory pathways in stem cell and immunobiology. We are particularly interested in understanding the establishment and maintenance of normal tissue homeostasis, supported by molecular interactions between members of the tissue microenvironment (e.g., epithelial, mesenchymal, and immune cells) and environmental factors (e.g., signals modulated by the microbiome). With the help of our collaborators, our lab aims to harness the power of multi-omics libraries to generate the novel data-driven hypothesis that can pave the way into future mechanistic and translational studies.
Are you ready to be a part of ground breaking research?
Our goal is to build a dynamic team dedicated to analyze and interpret multi-omics sequencing datasets in both basic and translational studies. This role will work within a collaborative team that aims to integrate phenotypic multi-omics data (transcriptomics, proteomics, metabolomics) into predictive and classification models. In this role, you will develop a wide range of computational analysis pipelines, from experimental design to data analyses and visualization to inform drug-discovery efforts and follow-up functional experiments. Therefore, proficiency is key in the analysis of several multi-omics data types (bulk and single-cell RNA-seq, ChIP-Seq, ATAC-seq, metagenomics, metatranscriptomics, spatial transcriptomics) and the use of bioinformatics software and databases.
A Project Scientist should be able to work independently while being an outstanding collaborator and very well-organized. The Project Scientist may be an ongoing member of a research team or may be employed for a limited period of time to contribute high-level skills to a specific research or creative program. Project Scientists are not required to carry out independent research or to develop an independent research reputation and do not have teaching responsibilities. Ordinarily, the Project Scientist will carry out research or creative programs as well as administration of day-to-day lab operations with supervision by a member of the Professorial Series. This position is an outstanding opportunity to do highly multidisciplinary research in a relevant biomedical problem within in collaboration with world-renowned IBD scientists. We have a number of ongoing projects and candidates will be encouraged to develop an individual plan and initiate their own collaborative research.
Additional Duties and Responsibilities:
May assist in preparation of grant proposals, submissions, publications and presentations but is not responsible for generating grant funds
May serve as PI for certain grants as approved by supervising member of the Professorial Series
May participate in publications and presentations as author or co-author
May develop, adapt and implement new research techniques and protocols
Assists in lab experiments
Analyzes, interprets, summarizes and compiles data
May lead or train Staff Research Associates and Research Fellows
Will assist in day-to-day laboratory activities
Appointees on an academic trajectory will be expected to commit a portion of their time to developing an independent range of research
Analyze and integrate multi-omic (transcriptomics, epigenomics, metagenomics) sequencing datasets into quantitative models
Interact continuously with our bench collaborators to guide and propose new experiments and use available data to its full potential
Conduct projects independently, maintain appropriate records and databases, and facilitate data access to wet-lab collaborators
Provide guidance and supervise the work of post-doctoral scholars and graduate students. Provide expert opinion and guidance on data analysis and experimental design
Participate and present research outputs in group meetings, collaborative meetings, project retreats and seminars. Present at national/international conferences
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.