The Gene Regulatory Evolution (GRE) Lab ( https://binhe-lab.org ) is hiring a postdoctoral researcher to work on the evolution of stress response in multiple clades of independently evolved commensal and opportunistic yeast pathogens in the same group as the model yeast S. cerevisiae . The postdoc position will be funded by an NIH grant aimed at understanding the general principles governing the evolution of stress response gene regulatory networks (GRNs) and its particular applications in the evolution of fungal pathogens, which are increasingly a threat in hospitals and senior living facilities. The work will involve working with a variety of model and non-model species, applying molecular and functional genomics, combined with single-cell measurements and computational modeling to understand the complex changes and consequences in a set of GRNs.
The GRE lab is part of a diverse group in the Biology Department at the University of Iowa, which provides a unique, integrative environment. The 28 research labs cover a wide variety of model organisms and spans molecular to ecological levels, with a particular strength in the study of stress responses in various contexts. University of Iowa is located in Iowa City, a UNESCO city of literature that features live culture, food, and high quality of living at a very reasonable cost.
The PI, Bin He, is a junior faculty member who obtained his Ph.D. from the Department of Ecology and Evolution at the University of Chicago, and conducted his postdoctoral research with Dr. Erin O'Shea at the FAS Center for Systems Biology at Harvard University. The GRE lab is committed to fostering a welcoming, supportive environment for all scientists, regardless of gender and ethnicity (see Biology Department statement on Diversity, Equity and Inclusion https://biology.uiowa.edu/about/diversity-equity-and-inclusion ). More information about the lab can be found at binhe-lab.org .The position is available immediately. An early start date is desirable but can be negotiated with the PI.
With over 31,000 students, the University of Iowa is one of the nation's top public research universities, a member of the Big Ten conference and the Association of American Universities. The University of Iowa is composed of eleven colleges and is known around the world for its balanced commitment to the arts, sciences, and humanities. It is home to one of the nation's largest academic medical centers and the pioneering Iowa Writers' Workshop. The University of Iowa promotes work/life integration and is located in the casual yet cosmopolitan environment of Iowa City, widely recognized as one of the country's most livable communities.