The Department of Chemistry, in the College of Liberal Arts and Sciences is seeking to hire a Postdoctoral Research Associate. The incumbent will lead the investigation of the roles played by RNA modifications in the biochemical mechanism of drug addiction. This project is part of a broad effort aimed at elucidating the functions of the epitranscriptome in neuromodulation and cellular memory. The project will be carried out at the University of Connecticut under Dr. D. Fabris' supervision.
DUTIES AND RESPONSIBILITIES
The incumbent will be responsible for the following tasks:
Conduct research aimed at elucidating the regulatory role of RNA modifications in the biochemical response of cells of the central nervous system to stimulation by neuromodulators and drugs of abuse.
Help elaborate hypothesis; design experimental strategy; perform and troubleshoot experiments.
Work with primary cells and maintain cell cultures; treat cells with selected neuromodulators and drugs of abuse; isolate RNA; perform analysis of RNA modifications.
Perform control experiments; bioassays; gene depletion, deletion, and mutagenesis.
Optimize and troubleshoot current experimental procedures, as needed.
Carry out data analysis and interpretation; generate summaries, graphs, and figures.
Write publications; participate in dissemination.
Train and lead a team of undergraduate and graduate research assistants.
The incumbent will be expected to use initiative in the planning and execution of the different tasks; to maintain the research productivity necessary to cultivate a presence in the scientific community; to develop a good understanding of how to best prioritize the various tasks according to the situation on the ground; to maintain the maximum possible flexibility to facilitate the solution of unforeseen problems. The incumbent will report directly to Dr. Fabris, the laboratory's principal investigator.
Ph.D. degree in life sciences-related fields with experience in experimental pharmacology, culturing cells, and performing bioassays. Direct experience with gene depletion, deletion, and mutagenesis is a must.
Start date for this position is anticipated for Fall 2020. The position is for an initial one-year appointment and is potentially renewable for a second year. Continuation beyond two years is contingent upon future external funding applications. Salary for this position will be determined by NIH guidelines.
Please apply online athttps://hr.uconn.edu/jobs, Staff Positions, Search #494673 to upload aresume,cover letter,and contact information forthree (3) professional references.
Employment of the successful candidate is contingent upon the successful completion of a pre-employment criminal background check.
This job posting is scheduled to be removed at 11:55 p.m. Eastern time on November 1, 2020.
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Internal Number: 494673-2276_1601028340
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