The Department of Oncology is seeking a full time Research Specialist II. The Rubens’ Laboratory is seeking a highly motivated Research Specialist to lead the development of new therapeutics targeting metabolic regulation of epigenetic drivers in aggressive pediatric brain tumors. Our laboratory has developed a unique niche in childhood cancer research at the cross-section of drug development, cancer metabolomics, and epigenetics. The research specialist will process and analyze metabolomics data, plan and analyze DNA methylation studies, and test the in vitro and in vivo efficacy of novel therapeutics in patient-derived cell models and mouse xenografts of pediatric brain tumors. The Rubens’ Laboratory exists within the larger Eye and Brain Tumor Research Laboratory in the State-of-the-Art Smith Research Building and is part of the Oncology Department at Johns Hopkins. This position requiresexperience in basic laboratory techniques in molecular biology and tissue culture.
Specific Duties and Responsibilities:
Develops experimental designs and has primary responsibility for planning, implementation, evaluation and interpretation results; design process may be in collaboration with the PI or completed independently.
Identifies problems, troubleshoots and analyzes variations observed and reported in regular testing protocols; modifies, refines or adapts techniques and procedures; modifies and/or adjusts quality control measures.
Coordinates and/or conducts multiple, concurrent assignments or a multi-faceted project.
Compiles, analyzes, and interprets research data Monitors documentation of results; reviews and recognizes documentation, which may lead to modification and adaptation of research methodologies; may collaborate with others; Adapts and/or modifies experimental methods based upon interpretation of data.
Conducts library research and participates in editing and preparing manuscripts, scientific illustrations, and computer graphics for publication.
Oversees and assures laboratory compliance with regulatory requirements and JHU standards, policies and procedures.
Works with research staff to prioritize and schedule projects.
Minimum Qualifications (mandatory):
BS/BA in biological sciences, chemistry or related field required.
Master’s degree in Biotechnology, preferred
Minimum of 2 years’ laboratory experience performing relevant techniques in a comparable setting required.
Advanced degree may substitute for experience to the extent permitted by the JHU equivalency formula.
JHU Equivalency Formula: 18 graduate degree credits may substitute for one year of experience.
Special Knowledge, Skills, and Abilities:
Culture and analysis of cell lines, immunohistochemistry, western blot
Performing established laboratory assays under the supervision of the faculty investigator
Operation of centrifuge, pH meter, analytical balance, incubator, spectrophotometer, light microscope, imaging systems and laminar flow hoods;
Familiarity with aseptic technique
Familiarity with theory behind experiments; ability to apply analytical skills to interpret experiments using positive and negative controls
Classified Title: Research Specialist II Working Title: Research Specialist II Role/Level/Range: ACRP/03/MB Starting Salary Range: $38,920 - $53,520 Employee group: Full Time Schedule: Monday-Friday/8:30am-5:00pm/40 hours Exempt Status: Exempt Location: 04-MD:School of Medicine Campus Department name: 10002936-SOM Onc Pediatric Oncology Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at email@example.com. For TTY users, call via Maryland Relay or dial 711.
The following additional provisions may apply depending on which campus you will work. Your recruiter will advise accordingly.
During the Influenza ("the flu") season, as a condition of employment, The Johns Hopkins Institutions require all employees who provide ongoing services to patients or work in patient care or clinical care areas to have an annual influenza vaccination or possess an approved medical or religious exception. Failure to meet this requirement may result in termination of employment.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
Equal Opportunity Employer Note: Job Postings are updated daily and remain online until filled.
Johns Hopkins University remains committed to its founding principle, that education for all students should be grounded in exploration and discovery. Hopkins students are challenged not just to learn but also to advance learning itself. Critical thinking, problem solving, creativity, and entrepreneurship are all encouraged and nourished in this unique educational environment. After more than 130 years, Johns Hopkins remains a world leader in both teaching and research. Faculty members and their research colleagues at the university's Applied Physics Laboratory have each year since 1979 won Johns Hopkins more federal research and development funding than any other university. The university has nine academic divisions and campuses throughout the Baltimore-Washington area. The Krieger School of Arts and Sciences, the Whiting School of Engineering, the School of Education and the Carey Business School are based at the Homewood campus in northern Baltimore. The schools of Medicine, Public Health, and Nursing share a campus in east Baltimore with The Johns Hopkins Hospital. The Peabody Institute, a leading professional school of music, is located on Mount Vernon Place in downtown Bal...timore. The Paul H. Nitze School of Advanced International Studies is located in Washington's Dupont Circle area.