The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Pennâ™s distinctive interdisciplinary approach to scholarship and learning.
Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.
The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.
The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.
The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the âœgo-toâ organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.
Continuation of all GTP positions is contingent upon funding.
Vector technology lies at the heart of GTP due to the contributions of the Wilson Lab. GTP has a long track record of success in developing novel vector technologies, manufacturing platforms and analytics as well as distributing vectors for research purposes. Once successful in the research environment, the vectors must be transferred to the clinic which requires expertise both regarding vector manufacturing and characterization. Our Vector Core is a state-of-the-art facility which provides vector-related materials and services in support of basic and translational research worldwide, produces vectors in support of IND-enabling research, develops and conducts GLP assays, oversee sCMO's in vector production and is expanding to perform state-of-the-art process development.
Due to significant growth, the Vector Core is looking for a new Executive Director of Analytics to lead a multidisciplinary team of testing and development staff responsible for assay development, quality control testing and vector release in support of research, IND-enabling studies, and clinical trials.
As the Executive Director, you will provide high-level leadership and provide the strategic vision as it pertains to vector characterization and quality control. You will oversee the activities of and develop/mentor a high-performing team in multiple functional functional areas which are inclusive of Assay Development (Cell-Based and Non-cell-based), Quality Control Testing (physical/structural, research, and GLP), and Quality Control Studies. You will develop and oversee the implementation of quantitative and qualitative metrics to assess performance as well as track/manage completion of objectives and projects. You will interface with external sponsors and internal teams to build strategies to support global initiatives, prepare presentations and other materials for external meetings, regulatory filings, publications, and grant applications. Working closely with the Executive Director of Vector Operations (EDVO) and Project Management, you will develop testing plans, budgets, and timelines, providing timely and accurate information to Management and Project Teams regarding the delivery of fully characterized vector for IND-enabling studies and clinical trials. You will develop analytical testing plans for clinical programs at CMOs and direct the transfer GLP assay technologies to CMO's and CRO's as well as pharmaceutical partners.
You will also work closely with the Senior Director, MS&T to understand newly developed or optimized manufacturing process and make determinations as to how analytics will support these programs.
â¢ MSc in Biochemistry, Biology, or related field and 7-10+ years of experience in analytical development and testing required.
â¢ PhD strongly preferred.
â¢ Minimum of 3 years of supervisory experience required.
â¢ Extensive knowledge of assay development, qualification and GxP regulations strongly preferred.
â¢ Experience in interactions with outside vendors, e.g., CMOs, CROs strongly preferred.
â¢ Experience in interactions with quality assurance and regulatory agencies preferred.
â¢ Ability to provide assay expertise to product development overseeing multiple programs required.
â¢ Self starter but also a strong desire to contribute and work collaboratively to achieve goals.
â¢ Success in roles requiring execution of multiple tasks while responding to multiple priorities. â¢ Highly functioning, detail-oriented, and analytical candidate who can think strategically.
â¢ Excellent oral/written communication skills required.
Job Location - City, State
Department / School
Perelman School of Medicine
$108,411.00 - $205,981.00
Affirmative Action Statement Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.
Special Requirements Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
Internal Number: JR00019095
About University of Pennsylvania
Penn has a long and proud tradition of intellectual rigor and pursuit of innovative knowledge, begun by Benjamin Franklin in 1740. That tradition lives today through the creativity, entrepreneurship, and engagement of our faculty, students, and staff. Academic life at Penn is unparalleled, with an undergraduate student body of 10,000 from every U.S. state and around the world. The entering class of 2015 is the most talented and diverse in Penn's history. Consistently ranked among the top 10 universities in the country, Penn welcomes an additional 10,000 students to our top-ranked graduate and professional schools.